Dyshidrotic eczema is a form of eczema that manifests as intensely itchy blisters that develop on the sides of the fingers, toes, palms, or soles. It can be caused by atopic dermatitis, contact dermatitis, or an id reaction (reaction to a skin infection or skin rash at another site). The condition is most common in adults, but can also affect children. Treatments include eliminating underlying causes and treating with prescription topical and/or oral medications.