Pemphigus is a rare group of autoimmune skin diseases that causes painful blisters to form on the skin and/or mucous membranes (lips, mouth, esophagus, nose, eyes, genitals). The different types of pemphigus include: pemphigus vulgaris, pemphigus vegetans, pemphigus foliaceus, endemic pemphigus, pemphigus erythematosus, and paraneoplastic pemphigus. These conditions are characterized by fragile blisters that easily rupture, leading to painful sores which are slow to heal. Treatment options include both topical and oral steroids as well as other systemic medications.